Metformin Could Help Prevent Some Breast Cancers

More study is needed to better understand whether there is a cause-effect relationship between metformin and cancer or whether the increased risk owes to an absence of protection from metformin, Sandler said.

The findings were published Jan. 29 in the Annals of Oncology.

Metformin has been hailed as something of a miracle for many diseases other than diabetes. Some research has linked it to a longer life span, reduced risk of vision loss and improved fertility in men and women.

The new study does not suggest that women without diabetes should take metformin to reduce breast cancer risk, said Dr. Pamela Goodwin, co-author of an editorial that accompanied the study. She’s a professor of medicine at the University of Toronto and former director of the Marvelle Koffler Breast Centre at Toronto’s Mount Sinai Hospital.

More research is needed to fully understand the link between diabetes and breast cancer and clarify what role metformin may play, Goodwin said.

Losing weight and engaging in regular physical activity can help lower diabetes risk, she said, adding this may have spillover benefits for breast cancer risk as well.

“If you have type 2 diabetes, get properly treated and in many cases, this means taking metformin. Make sure to get regular mammograms, too,” Goodwin said.

Dr. Sarah Cate, director of the special surveillance and breast program at the Blavatnik Family-Chelsea Medical Center at Mount Sinai in New York City, reviewed the findings.

“Certainly, metformin helps with weight loss, which is linked with estrogen-driven breast cancers, so this may explain why fewer patients on metformin got this type of breast cancer,” she said.

Both Cate and Goodwin noted that the finding on triple-negative breast cancer needs to be fleshed out.

“The number of patients who were found to have triple-negative breast cancer was small, so we cannot draw any practice-changing conclusions from it,” Cate said.

More information offers more information on risk factors for breast cancer.

SOURCES: Dale Sandler, PhD, chief, Epidemiology Branch, U.S. National Institute of Environmental Health Sciences, Research Triangle Park, N.C.; Pamela Goodwin, MD, MSc, professor, medicine, University of Toronto, and former director, Marvelle Koffler Breast Centre, Mount Sinai Hospital, Toronto; Sarah Cate, MD, assistant professor, surgery, Icahn School of Medicine, Mount Sinai, New York City, and director, special surveillance and breast program, Blavatnik Family-Chelsea Medical Center, Mount Sinai, New York City; Annals of Oncology, Jan. 29, 2021

Latest articles

Health Canada received more Johnson & Johnson data on same day as U.S. approval

Health Canada on Saturday received additional data required to inform its decision on Johnson & Johnson's COVID-19 vaccine — the same day the...

Here's What 25 Famous Actors Looked Like In The Beginning Of Their Careers Vs. Now

Young Sandra Oh was adorable!!!View Entire Post ›

Spacewalking astronauts prepare International Space Station for new solar arrays

Two spacewalking astronauts began preparing the International Space Station (ISS) for new solar arrays on Sunday (Feb. 28), battling tough bolts to kick...

23 Best Nintendo Switch Games for Every Player (2021)

The Switch is one of Nintendo's most successful and influential systems ever. There’s something unique about carrying a home-console-quality gaming device everywhere...

Related articles

Leave a reply

Please enter your comment!
Please enter your name here